41 publications

2021

• Schrankel, C. S., & Hamdoun, A. (2021). Early patterning of ABCB, ABCC, and ABCG transporters establishes unique territories of small molecule transport in embryonic mesoderm and endoderm. Developmental Biology, 472, 115-124. doi: 10.1016/j.ydbio.2020.12.021
• Warner, J. F., Lord, J. W., Schreiter, S. A., Nesbit, K. T., Hamdoun, A., & Lyons, D. C. (2021). Chromosomal-level genome assembly of the painted sea urchin Lytechinus pictus: A genetically enabled model system for cell biology and embryonic development. Genome Biology and Evolution, 13(4). doi: 10.1093/gbe/evab061
• Fleming, T. J., Schrankel, C. S., Vyas, H., Rosenblatt, H. D., & Hamdoun, A. (2021). CRISPR/Cas9 mutagenesis reveals a role for ABCB1 in gut immune responses to Vibrio diazotrophicus in sea urchin larvae. Journal of Experimental Biology, 224(7). doi: 10.1242/jeb.232272

2020

• Nicklisch, S. C. T., & Hamdoun, A. (2020). Disruption of small molecule transporter systems by Transporter-Interfering Chemicals (TICs). Febs Letters, 594(23), 4158-4185. doi: 10.1002/1873-3468.14005
• Nesbit, K. T., & Hamdoun, A. (2020). Embryo, larval, and juvenile staging of Lytechinus pictus from fertilization through sexual maturation. Developmental Dynamics. doi: 10.1002/dvdy.223
• Li, A. F., Espinoza, J., & Hamdoun, A. (2020). Inhibitory effects of neurotoxin beta-N-methylamino-L-alanine on fertilization and early development of the sea urchin Lytechinus pictus. Aquatic Toxicology, 221(105425). doi: 10.1016/j.aquatox.2020.105425

2019

• Gordon, W. E., Espinoza, J. A., Leerberg, D. M., Yelon, D., & Hamdoun, A. (2019). Xenobiotic transporter activity in zebrafish embryo ionocytes. Aquatic Toxicology, 212, 88-97. doi: 10.1016/j.aquatox.2019.04.013
• Nesbit, K. T., Fleming, T., Batzel, G., Pouv, A., Rosenblatt, H. D., Pace, D. A., ... Lyons, D. C. (2019). The painted sea urchin, Lytechinus pictus, as a genetically-enabled developmental model. Echinoderms, Pt A (pp. 105-123). London: Academic Press Ltd-Elsevier Science Ltd. doi: 10.1016/bs.mcb.2018.11.010
• Campanale, J. P., Hamdoun, A., Wessel, G. M., Su, Y. H., & Oulhen, N. (2019). Methods to label, isolate, and image sea urchin small micromeres, the primordial germ cells (PGCs). Echinoderms, Pt A (pp. 269-+). London: Academic Press Ltd-Elsevier Science Ltd. doi: 10.1016/bs.mcb.2018.11.007
• Schrankel, C. S., Gokirmak, T., Lee, C. W., Chang, G., & Hamdoun, A. (2019). Generation, expression and utilization of single-domain antibodies for in vivo protein localization and manipulation in sea urchin embryos. Echinoderms, Pt B (pp. 353-376). London: Academic Press Ltd-Elsevier Science Ltd. doi: 10.1016/bs.mcb.2018.11.005
• Shipp, L. E., Hill, R. Z., & Hamdoun, A. (2019). A teaching laboratory on the activation of xenobiotic transporters at fertilization of sea urchins. Echinoderms, Pt A (pp. 429-447). London: Academic Press Ltd-Elsevier Science Ltd. doi: 10.1016/bs.mcb.2018.11.013
• Foltz, K. R., & Hamdoun, A. (2019). Echinoderms, Part A. Echinoderms, Pt A (pp. XIX-XX). London: Academic Press Ltd-Elsevier Science Ltd.

2018

• Barron, M. E., Thies, A. B., Espinoza, J. A., Barott, K. L., Hamdoun, A., & Tresguerres, M. (2018). A vesicular Na+/Ca2+ exchanger in coral calcifying cells. PLOS ONE, 13(10). doi: 10.1371/journal.pone.0205367
• Mascuch, S. J., Boudreau, P. D., Carland, T. M., Pierce, N. T., Olson, J., Hensler, M. E., ... Gerwick, L. (2018). Marine natural product honaucin A attenuates inflammation by activating the Nrf2-ARE pathway. Journal of Natural Products, 81(3), 506-514. doi: 10.1021/acs.jnatprod.7b00734

2017

• Nicklisch, S. C. T., Bonito, L. T., Sandin, S., & Hamdoun, A. (2017). Mercury levels of yellowfin tuna (Thunnus albacares) are associated with capture location. Environmental Pollution, 229, 87-93. doi: 10.1016/j.envpol.2017.05.070
• Nicklisch, S. C. T., Bonito, L. T., Sandin, S., & Hamdoun, A. (2017). Geographic differences in persistent organic pollutant levels of yellowfin tuna. Environ Health Perspect, 125(6), 067014. doi: 10.1289/ehp518

2016

• Gokirmak, T., Campanale, J. P., Reitzel, A. M., Shipp, L. E., Moy, G. W., & Hamdoun, A. (2016). Functional diversification of sea urchin ABCC1 (MRP1) by alternative splicing. American Journal of Physiology-Cell Physiology, 310(11), C911-C920. doi: 10.1152/ajpcell.00029.2016
• Nicklisch, S. C. T., Rees, S. D., McGrath, A. P., Gökirmak, T., Bonito, L. T., Vermeer, L. M., ... Hamdoun, A. (2016). Global marine pollutants inhibit P-glycoprotein: Environmental levels, inhibitory effects, and cocrystal structure. Science Advances, 2(4). doi: 10.1126/sciadv.1600001
• Bonito, L. T., Hamdoun, A., & Sandin, S. A. (2016). Evaluation of the global impacts of mitigation on persistent, bioaccumulative and toxic pollutants in marine fish. Peerj, 4(e1573). doi: 10.7717/peerj.1573

2015

• Shipp, L. E., Hill, R. Z., Moy, G. W., Gokirmak, T., & Hamdoun, A. (2015). ABCC5 is required for cAMP-mediated hindgut invagination in sea urchin embryos. Development, 142(20), 3537-3548. doi: 10.1242/dev.126144

2014

• Gokirmak, T., Shipp, L. E., Campanale, J. P., Nicklisch, S. C. T., & Hamdoun, A. (2014). Transport in technicolor: Mapping ATP-binding cassette transporters in sea urchin embryos. Molecular Reproduction and Development, 81(9), 778-793. doi: 10.1002/mrd.22357
• Swartz, S. Z., Reich, A. M., Oulhen, N., Raz, T., Milos, P. M., Campanale, J. P., ... Wessel, G. M. (2014). Deadenylase depletion protects inherited mRNAs in primordial germ cells. Development, 141(16), 3134-3142. doi: 10.1242/dev.110395
• Campanale, J. P., Gokirmak, T., Espinoza, J. A., Oulhen, N., Wessel, G. M., & Hamdoun, A. (2014). Migration of sea urchin primordial germ cells. Developmental Dynamics, 243(7), 917-927. doi: 10.1002/dvdy.24133

2013

• Cole, B. J., Hamdoun, A., & Epel, D. (2013). Cost, effectiveness and environmental relevance of multidrug transporters in sea urchin embryos. Journal of Experimental Biology, 216(20), 3896-3905. doi: 10.1242/jeb.090522

2012

• Gokirmak, T., Campanale, J. P., Shipp, L. E., Moy, G. W., Tao, H. C., & Hamdoun, A. (2012). Localization and Substrate Selectivity of Sea Urchin Multidrug (MDR) Efflux Transporters. Journal of Biological Chemistry, 287(52), 43876-43883. doi: 10.1074/jbc.M112.424879
• Whalen, K., Reitzel, A. M., & Hamdoun, A. (2012). Actin polymerization controls the activation of multidrug efflux at fertilization by translocation and fine-scale positioning of ABCB1 on microvilli. Molecular Biology of the Cell, 23(18), 3663-3672. doi: 10.1091/mbc.E12-06-0438
• Shipp, L. E., & Hamdoun, A. (2012). ATP-binding cassette (ABC) transporter expression and localization in sea urchin development. Developmental Dynamics, 241(6), 1111-1124. doi: 10.1002/dvdy.23786
• Campanale, J. P., & Hamdoun, A. (2012). Programmed reduction of ABC transporter activity in sea urchin germline progenitors. Development, 139(4), 783-792. doi: 10.1242/dev.076752

2011

• Patel, S., Ramakrishnan, L., Rahman, T., Hamdoun, A., Marchant, J. S., Taylor, C. W., & Brailoiu, E. (2011). The endo-lysosomal system as an NAADP-sensitive acidic Ca(2+) store: Role for the two-pore channels. Cell Calcium, 50(2), 157-167. doi: 10.1016/j.ceca.2011.03.011

2009

• Bosnjak, I., Uhlinger, K. R., Heim, W., Smital, T., Franekic-Colic, J., Coale, K., ... Hamdoun, A. (2009). Multidrug Efflux Transporters Limit Accumulation of Inorganic, but Not Organic, Mercury in Sea Urchin Embryos. Environmental Science & Technology, 43(21), 8374-8380. doi: 10.1021/es901677r
• Hamdoun, A. (2009). Reduced intracellular accumulation of calcein by overexpression of fluorescent protein fusions of the multidrug transporter Sp-ABCB1a, in sea urchin (Strongylocentrotus purpuratus) embryos.. Mount Desert Island Biological Laboratory Bulletin, 48, 59-62.

2008

• Epel, D., Luckenbach, T., Stevenson, C. N., Macmanus-Spencer, L. A., Hamdoun, A., & Smital, T. (2008). Efflux transporters: Newly appreciated roles in protection against pollutants. Environmental Science & Technology, 42(11), 3914-3920. doi: 10.1021/es087187v

2007

• Hamdoun, A., & Epel, D. (2007). Embryo stability and vulnerability in an always changing world. Proceedings of the National Academy of Sciences of the United States of America, 104(6), 1745-1750. doi: 10.1073/pnas.0610108104

2006

• Roepke, T. A., Hamdoun, A. M., & Cherr, G. N. (2006). Increase in multidrug transport activity is associated with oocyte maturation in sea stars. Development Growth & Differentiation, 48(9), 559-573. doi: 10.1111/j.1440-169x.2006.00893.x
• Goldstone, J. V., Hamdoun, A., Cole, B. J., Howard-Ashby, M., Nebert, D. W., Scally, M., ... Stegeman, J. J. (2006). The chemical defensome: Environmental sensing and response genes in the Strongylocentrotus purpuratus genome. Developmental Biology, 300(1), 366-384. doi: 10.1016/j.ydbio.2006.08.066
• Sea Urchin Genome Sequencing Consortium (2006). Research article - The genome of the sea urchin Strongylocentrotus purpuratus. Science, 314(5801), 941-952. doi: 10.1126/science.1133609
• Epel, D., Cole, B., Hamdoun, A., & Thurber, R. V. (2006). The sea urchin embryo as a model for studying efflux transporters: Roles and energy cost. Marine Environmental Research, 62, S1-S4. doi: 10.1016/j.marenvres.2006.04.062

2004

• Hamdoun, A. M., Cherr, G. N., Roepke, T. A., & Epel, D. (2004). Activation of multidrug efflux transporter activity at fertilization in sea urchin embryos (Strongylocentrotus purpuratus). Developmental Biology, 276(2), 452-462. doi: 10.1016/j.ydbio.2004.09.013
• Smital, T., Luckenbach, T., Sauerborn, R., Hamdoun, A. M., Vega, R. L., & Epel, D. (2004). Emerging contaminants--pesticides, PPCPs, microbial degradation products and natural substances as inhibitors of multixenobiotic defense in aquatic organisms. Mutation research, 552(1-2), 101-17. doi: 10.1016/j.mrfmmm.2004.06.006

2003

• Hamdoun, A. M., Cheney, D. P., & Cherr, G. N. (2003). Phenotypic plasticity of HSP70 and HSP70 gene expression in the Pacific oyster (Crassostrea gigas): Implications for thermal limits and induction of thermal tolerance. Biological Bulletin, 205(2), 160-169. doi: 10.2307/1543236

2002

• Hamdoun, A. M., Griffin, F. J., & Cherr, G. N. (2002). Tolerance to biodegraded crude oil in marine invertebrate embryos and larvae is associated with expression of a multixenobiotic resistance transporter. Aquatic Toxicology, 61(1-2), 127-140. doi: 10.1016/s0166-445x(02)00050-4